Emerging Pathogens Laboratory

The University of Iowa, College of Public Health

Department of Epidemiology


Human Viral Isolate Reference Sheet

 

 

Catalogue Item Name: Ad 7h-1                             

 

Classification: Adenovirus serotype 7        Strain: genotype 7h

 

Passage: 3     Culture Host: A549 cells     Time period Host Cells Infected:  3-5 days

 

Original Source Information: This isolate was collected in December 1999 from the nasal wash of a 1-year old male in an Iowa hospital.

 

Method of Identification Confirmation: A virology laboratory performed cell culture and monoclonal fluorescent antibody staining confirmation.  The Emerging Pathogens Laboratory repeated cell culture using A549 cells, and also performed microneutralization serotyping using antisera 1-5, 7, and 21.  The isolate was determined to be serotype 7.  Restriction enzyme analysis of the purified DNA with BamHi revealed a pattern consistent with genotype 7h. (Patterns were compared to five prototype adenovirus serotype 7 of genotypes:  7b, 7d2, 7h, 7p, and 7a, obtained from the CDC)

 

Reference:  M. Noda, T. Yoshida, T. Sakaguchi, Y. Ikeda, K. Yamaoka, and T. Ogino. 2002.  Molecular and Epidemiological Analyses of Human Adenovirus Type 7 Strains Isolated from the 1995 Nationwide Outbreak in Japan.  J. Clin. Microbiol.  40:140-145.

 

Biosafety Level: 2

 

Permits/ Forms:  A University of Iowa Material Transfer Agreement form must be accepted prior to distributing this specimen.  The point of contact is:


Dwight Ferguson
Emerging Pathogens Laboratory
University of Iowa
2501 Crosspark Rd
Coralville, IA 52241
ph:  319 335-4983
fax:  319 335-4984
cph-CEIDcatalog@uiowa.edu