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| Human metapneumovirus
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Very little
is known about this newly described virus of the
Paramyxoviridae family. Early data suggest
it is genetically most similar to the avian pneumovirus
and hence its name.
The virus is a single stranded, RNA, negative
sense virus. Early assessments suggest that the
virus may be similar to respiratory syncytial
virus in having two distinct genotypes and a similar
epidemiology. Early data suggest that the virus
can cause severe respiratory disease and death,
that reinfections may occur and that all ages
may be susceptible to infections.
Pubmed
entries
Genebank
entry
Webcast:
The New Human Metapneumovirus by
Albert Osterhaus, University of Rotterdam, Rotterdam,
The Netherlands
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Negative-stain
electron micrographs of human metapneumovirus.
Center image shows 5 pleomorphic HMPV particles.
Note the projections along the periphery of the
viruses. The images in
the upper right and lower left corners are, respectively,
of the nucleocapsid and filamentous rod–like
particle. Staining was done with 2% phosphotungstic
acid.
Photograph by Dr. Charles Humphrey
of CDC/NCID/IDPA
Published in JID 2002;185:1660-3 |
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