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Research projects

 

Active Projects:

Chris Atchison (PI) 10/01/01 - 9/30/04
Iowa Center for Public Health Preparedness
CDC/ASPH Cooperative Agreement
The Iowa Center provides a need appropriate regimen of public health practice education to a range of professions with responsibility for responding to any potential or actual public health emergency.

Leslie Dennis (PI) 1/01/04-12/31/06
Sexually Transmitted Infections as a Risk Factor for Prostate Cancer among Military
US Department of Defense
This is a nested case-control study of the association of sexually transmitted infections and prostate cancer

Gregory C. Gray (PI) 6/15/04– 4/14/09
National Surveillance for Emerging Adenovirus Infections
NIH / NIAID R01 AI053034
This 5-year study will establish a 15-site, national laboratory surveillance system and risk factor analyses for emerging adenovirus strains.

Tara C. Smith (PI) 3/1/05-2/28/07
Analysis of Hypervariable Genes in Streptococcus agalactiae
College of Public Health-Carver College of Medicine New Investigator Research Awards
Searches for genetic predictors for severe disease

Gregory C. Gray (PI) 11/01/05-10/31/06
Randomised, Double Blind, Multicentre, Placebo Controlled Phase III Study of the Safety and Tolerability Following Administration of Live Attenuate JE Vaccine (ChimeriVax®- JE)
Acambis

Gregory C. Gray (PI) 08/15/2006 - 07/31/2010
Prospective Studies of Avian Influenza Transmission in Asia
NIH / NIAID-1 R01 AI068803-01
Prospective study of 1600 poultry workers for avian influenza A infections.

Ghazi Kayali (PI and graduate student) 2/1/07-5/31/08
Viral Zooanthroponoses from Turkeys to Humans
Center funds
Study of turkey workers for previous avian virus infections.

Whitney Baker, MPH (PI)
Seroepidemiological study of Brucella canis infections in man
Center funds
Study of puppy farm workers for previous B. canis infections.

Gregory C. Gray (PI)
Light Diagnostics Human Metapneumovirus Direct Immunoflourescence Assay
Millipore Inc.


Projects under Review:

 

 

Completed Projects:

Gregory C. Gray (PI) 7/1/02-3/10/05
Surveillance for Emerging Viral Respiratory Pathogens in South America
International Programs, University of Iowa
The goal of this study is to build upon a successful South American influenza surveillance system in examining the epidemiology of emerging adenoviral and human metapneumovirus infections.

Gregory C. Gray (PI) 9/15/02-3/31/03
Becton Dickinson
Clinical Evaluation of a New System for the Detection of the Chlamydiaceae family, Legionella pneumophila, and Mycoplasma pneumoniae from Clinical Respiratory Specimens - This multisite study will evaluate a new system for the detection of the Chlamydiaceae family, Legionella pneumophila, and Mycoplasma pneumoniae. A secondary objective (our site alone) will be to search for viral causes of pneumonia, including emerging genotypes of adenovirus and the newly described human metapneumonivirus.

Gregory C. Gray (PI) 10/18/02-6/01/03
Merck & Company
Merck V21 Protocol 016 - this is a phase II double-blind, randomized, multicenter trial of a combination vaccine among healthy children. The study is being carried out in the Prevention Intervention Center at UIHC.

Ralph Wilmoth (PI) 11/15/02-6/30/05
A Retrospective Study of a Pertussis Outbreak Among Iowa City School District Students
This is a retrospective epidemiological study of the 2000-2001 outbreak using the Iowa City School District's reportable disease case data, Johnson County student vaccine data, University of Iowa Geography Department's Geographical Information System (GIS) data, and laboratory bacterial fingerprinting techniques.

Bradley E. Britigan (PI) 9/01/03-08/31/04
Biodefense: Analysis of Human Lung-Host-Pathogen Interaction
Response to NIH-NIAID-AI-02-050
This is a planning grant drafted to develop a regional center of excellence for biodefense and emerging pathogens for US region VII.

Gregory C. Gray (PI) 3/1/03-2/28/05
Evaluations of Rapid Diagnostic Tests for Respiratory Viruses
SA Scientific
Research to compare rapid diagnostic tests with viral culture.

Kendall Myers (Graduate Student) Gregory C. Gray (PI) 7/1/03-6/30/04
Are Iowa’s Meat Processing Workers at Increased Risk of Zoonotic Infections?
Center for Health Effects of Environmental Contamination University of Iowa
This pilot study may shed significant light upon previously unexamined environmental health risks for meat processing workers in Iowa and throughout the United States.

Gregory C. Gray (PI) 2/15/04-12/31/06
Do Veterinarians Have Haematologic Evidence of Zoonotic Infections?
This is a cross-sectional, haematologic study of up to 1000 veterinarians for evidence of previous infection with West Nile virus, zoonotic influenza A, avian pneumovirus, or PERV.

Gregory C. Gray (PI) 3/01/04-2/28/06
Human Metapneumovirus: Identifying High Risk Populations and Viral Genotype Variation
NIH / NIAID R03 AI054570
The investigators will determine the prevalence, genotypes, and risk factors for clinical human metapneumovirus infections at a Midwestern regional medical center.

Gregory C. Gray (PI) 12/1/03-5/1/04
Directigen EZ Flu A+B Clinical Evaluation for Detection of Influenza A and B: Dry Swab Evaluation
Becton Dickinson
Research to compare rapid diagnostic tests with viral culture.

Gregory C. Gray (PI) 10/1/03-10/1/04
Binax Adenovirus and Parinfluenza Clinical Study
Binax
Research to compare rapid diagnostic tests with viral culture.

Gregory C. Gray (PI) 12/11/03-12/1/04
Hawkeye Flu Study
CDC
Web-based study to evaluate influenza vaccine effectiveness among 3,000 students

Sandy Olson (Graduate Student) Gregory C. Gray (PI) 7/25/04-6/30/05
Poultry Handling Safety Study
Epidemiology Department funds
Pilot study of occupational risks for avian influenza at county fairs

James Gill (PI) 6/1/04-5/31/06
Are Iowans Exposed to Wild Ducks, Geese, and Game Birds
at Risk of Avian Influenza Infections?
Center for Health Effects of Environmental Contamination University of Iowa
This is a cross-sectional pilot study of occupational groups exposed to ducks, geese, and game birds

Peter Weyer (PI) 8/20/04 - 6/30/06
Iowa Beach Study
Center for Health Effects of Environmental Contamination University of Iowa & Iowa Department of Natural Resources
Prospective web-based study of fresh water beach contamination and self-reported gastrointestinal illness

Alex Ramirez (graduate student) Gregory C. Gray (PI) 10/15/04-5/31/05
Cross-sectional pilot study to Identify Prevalence of Zoonotic Influenza among Swine and Poultry Confinement Workers

Center funds
Pilot study of occupational risks for avian influenza.

Gregory C. Gray (PI) 3/01/04-12/31/06
Population-based Surveillance for Zoonotic Influenza A
NIH / NIAID- R21 AI059214-01
This is a 2-year prospective study of zoonotic influenza infections among 750 rural Iowans

Kerry Leedom (PI and graduate student) 3/1/05-6/1/06
Are Persons Occupationally Exposed to Horses at Risk of Infection from Equine Influenza?
Center funds
Pilot study of occupational risks for equine influenza

Ernesto Ortiz (PI and graduate student) 7/1/05-5/31/07
Occupational risk of avian influenza infection among Peruvian poultry workers
Center funds
Study of Peruvian poultry workers for previous avian influenza infection.

Gregory C. Gray (PI) 10/1/05-9/30/06
A Randomized, Double-blind, Placebo Controlled Trial to Evaluate the Efficacy of Fluviral® Influenza vaccine in Human Adults 18 to 49 Years of Age, Protocol, No. IDB-707-106
ID Biomedical