Active Projects:

Gregory C. Gray (PI) 6/15/04– 4/14/09
National Surveillance for Emerging Adenovirus Infections
NIH / NIAID R01 AI053034
This 5-year study will establish a 15-site, national laboratory surveillance system and risk factor analyses for emerging adenovirus strains.

Gregory C. Gray (PI) 08/15/2006 - 07/31/2010
Prospective Studies of Avian Influenza Transmission in Asia
NIH / NIAID-1 R01 AI068803-01
Prospective study of 1600 poultry workers in Cambodia and Thailand for avian influenza A infections.

Gregory C. Gray (PI) 02/01/2008 - 2013
Identifying Risk Factors for Zoonotic Influenza Transmission
US Dept of Defense Global Emerging Infections Surveillance
Avian Influenza/Pandemic Influenza Program Congressional Supplement W81XWH-06-C-0414
Prospective study of 1450 animal workers in Nigeria, Romania, and Mongolia for zoonotic influenza A infections.

Gregory C. Gray (PI) 05/01/2008 - 04/30/2010
Swine Influenza at Swine Shows
CDC & Univ of Minnesota's International Cooperative Zoonotic Influenza Research Center
Prospective study of 300 swine show handlers and their pigs for evidence of swine influenza and MRSA infections.

Gregory C. Gray (PI) 2008 - 2012
Prospective Study of Bird Banders for Evidence of Avian Influenza Virus Infections
NIH & Univ of Minnesota's Center of Excellence for Influenza Research and Surveillance
A prospective, risk factor study of US bird banders for previous and acute infection with H4-H11 avian influenza viruses.

Gregory C. Gray (PI)
Surveillance for Avian Influenza Among Birds in Romania and Mongolia
St. Jude Children's Research Hospital NIAID Center for Excellence for Influenza Research and Surveillance
Search for influenza among migrating and aquatic birds.

Gregory C. Gray (PI) and Gary Heil
Evaluation of a DNA Chip for Rapid Identification of Influenza A
Supplemental funding under NIH/NIAID-1 RO1 AI068803-01
Programming and evaluation of the Mchip's neural network.

Fionna Burnell and Gregory C. Gray (Co-PIs) 2008
Seroepidemiological Study of Human Exposure to Equine Influenza in Queensland, Australia
A cross-sectional, seroepidemiological study of humans who work with horses to see if they have evidence of exposure to the equine influenza virus.

Tara C. Smith (PI) August 2008-July 2009
Investigation of Methicillin-Resistant Staphylococcus aureus (MRSA) Colonization in Swine Farms and Farmers.
National Pork Board
This project will investigate how common MRSA is in Iowa’s swine and swine farmers, examining both conventional and organic/antibiotic-free farms.

Tara C. Smith (PI) October 2008-September 2009
Methicillin-Resistant Staphylococcus aureus (MRSA) in Rural Iowa.
Great Plains Center for Agricultural Health.
This project will examine the prevalence of MRSA in Iowa’s rural areas, and include examination of individuals and animals (swine, cattle, chickens).

Tara C. Smith (PI)
Are fair Swine Colonized with MRSA?
This project is examining the prevalence and molecular types of MRSA in state fair swine.

Tara C. Smith (PI)
Environmental and Air-Borne MRSA in Swine Barns
This project is examining MRSA in swine barns quantitation of bacterial levels in the air within and outside of facilities; particle size of bacterial particles; and presence in manure pits and water sources near the barns.

Tara C. Smith (PI)
Comparison of Chromogenic Agars for MRSA Isolation From Swine
This project is examining 3 different chromogenic agars to determine variability in detection of MRSA from swine nasal samples.

Tara C. Smith (PI)
How Common is MRSA in Meat Samples?
Examination of retail meat (beef, pork, and chicken) for MRSA contamination

Kerry Leedom-Larson (PhD Candidate) and Tara C. Smith (Co-PIs)
MRSA and Pathogens in Pork Production Shower Facilities
Examination of environmental contamination with MRSA in shower facilities in swine barns. Great Plains Center for Agricultural Health. October 2008-September 2009

Gregory C. Gray (PI) and Margaret Chorazy (PI and PhD Candidate) May 1, 2008 - June 30,2009
Evaluation of Adenovirus Real-Time and Conventional PCR Assays to Detect Fecal Contamination in Water and to Identify Its Source
Center for Health Effects of Environmental Contamination (CHEEC), University of Iowa
The primary objective of this study is to develop a set of tools (species-specific primer sets and quantitative real-time PCR assays) to detect adenoviruses resulting from fecal contamination in surface water.

Margaret Chorazy (PI and PhD Candidate)
Importance of Human Adenoviruses and Human Bocavirus in Mixed Enteric Infections
Center funds
The primary objective of this study is to investigate the association of polymicrobial gastroenteritis and severity of illness, with an emphasis on mixed infections including adenoviruses and/or human bocavirus.

Whitney Baker (PI and PhD student)
Seroepidemiological Study of Canine Zoonoses in People Occupationally Exposed to Dogs
Center funds
Study of breeders, veterinarians, shelter workers, and persons involved in dog racing for previous Brucella canis, canine influenza virus, and canine respiratory coronavirus infections.

Erin Moritz (PhD Student) and Tara Smith (Co-PIs)
Risk of Colonization with Staphylococcus aureus and Streptococcus pneumoniae in Childcare Personnel
University of Iowa Heartland Center for Occupational Health and Safety (CDC)
This project will evaluate the hypotheses that employment in a daycare center is a risk factor for colonization with S. aureus and S. pneumoniae and that daycare centers serve as reservoirs for these organisms. 

 


 

Completed Projects:

Tara C. Smith (PI)
Seroprevalence of Streptococcus suis antibodies in swine workers.
This study investigated prior exposure to Streptococcus suis in individuals working in close contact with live swine.

Ghazi Kayali (PI and graduate student) 2/1/07-5/31/08
Viral Zooanthroponoses from Turkeys to Humans
Center funds
Study of turkey workers for previous avian virus infections.

Ernesto Ortiz (PI and graduate student) 7/1/05-5/31/07
Occupational Risk of Avian Influenza Infection Among Peruvian Poultry Workers
Center funds
Study of Peruvian poultry workers for previous avian influenza infection.

Tara C. Smith (PI) 3/1/05-2/28/07
Analysis of Hypervariable Genes in Streptococcus agalactiae
College of Public Health-Carver College of Medicine New Investigator Research Awards
Searches for genetic predictors for severe disease

Gregory C. Gray (PI) 3/01/04-12/31/06
Population-based Surveillance for Zoonotic Influenza A
NIH / NIAID- R21 AI059214-01
This is a 2-year prospective study of zoonotic influenza infections among 750 rural Iowans

Leslie Dennis (PI) 1/01/04-12/31/06
Sexually Transmitted Infections as a Risk Factor for Prostate Cancer among Military
US Department of Defense
This is a nested case-control study of the association of sexually transmitted infections and prostate cancer.

Gregory C. Gray (PI) 2/15/04-12/31/06
Do Veterinarians Have Haematologic Evidence of Zoonotic Infections?
This is a cross-sectional, haematologic study of up to 1000 veterinarians for evidence of previous infection with West Nile virus, zoonotic influenza A, avian pneumovirus, or PERV.

Gregory C. Gray (PI) 11/01/05-10/31/06
Randomised, Double Blind, Multicentre, Placebo Controlled Phase III Study of the Safety and Tolerability Following Administration of Live Attenuate JE Vaccine (ChimeriVax®- JE)
Acambis

Gregory C. Gray (PI) 10/1/05-9/30/06
A Randomized, Double-blind, Placebo Controlled Trial to Evaluate the Efficacy of Fluviral® Influenza vaccine in Human Adults 18 to 49 Years of Age, Protocol, No. IDB-707-106
ID Biomedical

Peter Weyer (PI) 8/20/04 - 6/30/06
Iowa Beach Study
Center for Health Effects of Environmental Contamination University of Iowa & Iowa Department of Natural Resources
Prospective web-based study of fresh water beach contamination and self-reported gastrointestinal illness.

Kerry Leedom (PI and PhD candidate) 3/1/05-6/1/06
Are Persons Occupationally Exposed to Horses at Risk of Infection from Equine Influenza?
Center funds
Pilot study of occupational risks for equine influenza

James Gill (PI) 6/1/04-5/31/06
Are Iowans Exposed to Wild Ducks, Geese, and Game Birds at Risk of Avian Influenza Infections?
Center for Health Effects of Environmental Contamination University of Iowa
This is a cross-sectional pilot study of occupational groups exposed to ducks, geese, and game birds.

Gregory C. Gray (PI) 3/01/04-2/28/06
Human Metapneumovirus: Identifying High Risk Populations and Viral Genotype Variation
NIH / NIAID R03 AI054570
The investigators will determine the prevalence, genotypes, and risk factors for clinical human metapneumovirus infections at a Midwestern regional medical center.

Sandy Olson (Graduate Student) Gregory C. Gray (PI) 7/25/04-6/30/05
Poultry Handling Safety Study
Epidemiology Department funds
Pilot study of occupational risks for avian influenza at county fairs

Ralph Wilmoth (PI) 11/15/02-6/30/05
A Retrospective Study of a Pertussis Outbreak Among Iowa City School District Students
This is a retrospective epidemiological study of the 2000-2001 outbreak using the Iowa City School District's reportable disease case data, Johnson County student vaccine data, University of Iowa Geography Department's Geographical Information System (GIS) data, and laboratory bacterial fingerprinting techniques.

Alex Ramirez (graduate student) Gregory C. Gray (PI) 10/15/04-5/31/05
Cross-sectional pilot study to Identify Prevalence of Zoonotic Influenza among Swine and Poultry Confinement Workers

Center funds
Pilot study of occupational risks for avian influenza.

Gregory C. Gray (PI) 7/1/02-3/10/05
Surveillance for Emerging Viral Respiratory Pathogens in South America
International Programs, University of Iowa
The goal of this study is to build upon a successful South American influenza surveillance system in examining the epidemiology of emerging adenoviral and human metapneumovirus infections.

Gregory C. Gray (PI) 3/1/03-2/28/05
Evaluations of Rapid Diagnostic Tests for Respiratory Viruses
SA Scientific
Research to compare rapid diagnostic tests with viral culture.

Gregory C. Gray (PI) 12/1/03-5/1/04
Directigen EZ Flu A+B Clinical Evaluation for Detection of Influenza A and B: Dry Swab Evaluation
Becton Dickinson
Research to compare rapid diagnostic tests with viral culture.

Kendall Myers (Graduate Student) Gregory C. Gray (PI) 7/1/03-6/30/04
Are Iowa’s Meat Processing Workers at Increased Risk of Zoonotic Infections?
Center for Health Effects of Environmental Contamination University of Iowa
This pilot study may shed significant light upon previously unexamined environmental health risks for meat processing workers in Iowa and throughout the United States.

Bradley E. Britigan (PI) 9/01/03-08/31/04
Biodefense: Analysis of Human Lung-Host-Pathogen Interaction
Response to NIH-NIAID-AI-02-050
This is a planning grant drafted to develop a regional center of excellence for biodefense and emerging pathogens for US region VII.

Chris Atchison (PI) 10/01/01 - 9/30/04
Iowa Center for Public Health Preparedness
CDC/ASPH Cooperative Agreement
The Iowa Center provides a need appropriate regimen of public health practice education to a range of professions with responsibility for responding to any potential or actual public health emergency.

Gregory C. Gray (PI) 10/1/03-10/1/04
Binax Adenovirus and Parinfluenza Clinical Study
Binax
Research to compare rapid diagnostic tests with viral culture.

Gregory C. Gray (PI) 12/11/03-12/1/04
Hawkeye Flu Study
CDC
Web-based study to evaluate influenza vaccine effectiveness among 3,000 students

Gregory C. Gray (PI) 9/15/02-3/31/03
Becton Dickinson
Clinical Evaluation of a New System for the Detection of the Chlamydiaceae family, Legionella pneumophila, and Mycoplasma pneumoniae from Clinical Respiratory Specimens - This multisite study will evaluate a new system for the detection of the Chlamydiaceae family, Legionella pneumophila, and Mycoplasma pneumoniae. A secondary objective (our site alone) will be to search for viral causes of pneumonia, including emerging genotypes of adenovirus and the newly described human metapneumonivirus.

Gregory C. Gray (PI) 10/18/02-6/01/03
Merck & Company
Merck V21 Protocol 016 - this is a phase II double-blind, randomized, multicenter trial of a combination vaccine among healthy children. The study is being carried out in the Prevention Intervention Center at UIHC.