Fungicides are applied to both corn and soybeans at various times during the growing season. Corn is typically sprayed V6-V7 stage (6-7 fully developed leaves with leaf collar) and again at full tassel. Soybeans can be sprayed at full flower (R2) through first pod stage (R3). Fungicides are often applied aerially.
Acute toxicity to fungicides is generally considered to be low. Fungicides can be irritating to the skin and eyes and cause sneezing, coughing and throat irritation. Azoxystrobin is one common active ingredient that may irritate eyes, skin, and respiratory tract. Copper compounds can cause a metallic taste, nausea, vomiting, and intestinal pain. Sulfur can also cause diarrhea.
In 2007, 33 people, including 27 migrant workers, in Iowa became ill after Pyraclostrobin fungicide drifted from an aerial sprayer into the field where they were working. All cases were categorized as being of low severity; the most common symptom was respiratory irritation and chest pain.