Real-world evidence, Learning Health Systems, pragmatic trials, patient-centered outcomes research, and medical product safety and effectiveness are contemporary topics for which clinical and health services epidemiologists have much to offer.

Students with the following interests and are encouraged to explore this research interest areas area, regardless of degree program:

• pharmacoepidemiology
• comparative effectiveness research
• health services epidemiology, hospital epidemiology
• clinical investigation, clinical epidemiology
• a variety of health conditions and patient populations such as infectious diseases, chronic diseases, injuries, older adults, maternal and child health

Faculty members primarily working in this area

Ryan Carnahan	Pharmacoepidemiology, aging, psychiatry, dementia and delirium, long-term care, stakeholder engagement
Mary Charlton	Cancer surveillance and epidemiology, access to care, rural health disparities
Elizabeth Chrischilles	Pharmacoepidemiology, comparative effectiveness research, pragmatic trials, cancer outcomes research
Sarah Nash	Cancer surveillance, epidemiology, and prevention; Health services research with a specific focus on cancer screening; Community-engaged research methods
Michael O’Rorke	Molecular epidemiology, biomarkers of treatment response and prognostication, clinical epidemiology, cancer epidemiology, pharmacoepidemiology
James Torner	Clinical trial methods, neuroepidemiology, musculoskeletal disorders

Collaborating faculty

Catherine Bradley	Urogynecology and reconstructive pelvic surgery, patient-reported outcomes, psychiatric correlates of urinary incontinence
Lauris Kaldjean	Bioethics, end of life decision-making, goals of care, philosophy and religious beliefs in clinical decision-making
Enrique Leira	Acute stroke management, evidence-based strategies to improve stroke management in rural areas, novel strategies to enable rural patients to participate in stroke trials
Barcey Levy	Family medicine, preventive health care, colon cancer screening, practice-based research networks
Brian Lund	Pharmacoepidemiology and drug safety, mental health, older adults
Nicholas Mohr	Emergency medicine, rural telehealth, predictors and outcomes of interhospital transfer time
Eli Perencevich	Infectious diseases, health services epidemiology, cost-effectiveness of infection control interventions
Philip Polgreen	Computational epidemiology, sensors and personal devices for monitoring disease activity and health behaviors
Kathleen Schneider	Chronic disease management, Medicare and Medicaid program data, quality of care studies
Marin Schweizer	Infectious disease clinical epidemiology, infection prevention and control, meta-analysis and systematic reviews
Carolyn Turvey	Psychiatric epidemiology, access to care, patient portals, telemedicine

Emeritus faculty

Jennifer Robinson	Clinical trials of atherosclerosis modifying agents, cardiovascular disease epidemiology, clinical practice guidelines
Robert Wallace	Clinical epidemiology, aging, multi-morbidity, disabling illness, clinical trials
Richard Hoffman	General internal medicine, cancer prevention and control, patient decision-making, comparative effectiveness

Featured Courses

• EPID:5500 Introduction to Clinical Epidemiology
• EPID:6910 Pharmacoepidemiology
• EPID:6920 Applied Administrative Data Analysis
• EPID:5214 Meta-analysis of Epidemiologic Studies
• EPID:6900 Intervention and Clinical Trials
• EPID:6950 Clinical Research Ethics

Learning Objectives

Students interested in clinical and health services epidemiology are preparing for a career in which they will:

• Evaluate need, use, performance and outcomes of health and healthcare products, procedures, interventions, services and programs
• Advance methods for quantifying health effects of products, interventions, services and programs
• Contribute to optimizing health of patients
• Inform clinical and healthcare practice and policy
• Collaborate and lead multidisciplinary teams to design and conduct observational and interventional research
• Be competent in a family of related research fields including: outcomes research, health services research, clinical epidemiology, pharmacoepidemiology, and clinical effectiveness research

Recommended Plan of Study for the Clinical and Health Services Research Interest Area PhD Elective Requirement

course #	course name	s.h.	semester(s) offered*
Students interested in clinical and health services epidemiology will take the following four courses:
EPID:5500	Introduction to Clinical Epidemiology	3 s.h.	Fall
EPID: 6910	Pharmacoepidemiology and Comparative Effectiveness Research	3 s.h.	Fall even years
EPID:6920	Applied Administrative Data Analysis	2 s.h.	Fall
HMP:4000	Introduction to US Healthcare System	3 s.h.	Spring, Summer (online)
In addition, students will complete at least 14 s.h. from the following recommended courses. Students should select courses in consultation with their advisor to reflect their research interest area (e.g. pharmacoepi, comparative effectiveness, clinical trials, health services research, or outcomes research).
EPID:5214	Meta-analysis of Epidemiologic Studies	3 s.h.	Spring odd years
EPID:5560	Introduction to Molecular Epidemiology	3 s.h.	Spring odd years
EPID:6071	Social Epidemiology	3 s.h.	Fall
EPID:6900	Design of Intervention and Clinical Trials	3 s.h.	Fall
BIOS:5310	Research Data Management	3 s.h.	Fall, Spring
BIOS:6210	Applied Survival Analysis	3 s.h.	Spring
BIOS:6310	Introductory Longitudinal Data Analysis	3 s.h.	Fall
EPID:6420	Survey Design and Analysis	3 s.h.	Spring even years
BIOS:6610	Statistical Methods in Clinical Trials	3 s.h.	Spring
BIOS:6650	Causal Inference	3 s.h.	Spring
CBH:6205	Designing and Implementing Interventions	3 s.h.	Fall
EPLS:5165	Introduction to Program and Project Evaluation	3 s.h.	Spring
GEOG:4150	Health and Environment: GIS Applications	3 s.h.	Fall
HMP:7550	Cost Effectiveness and Decision Analysis	3 s.h.	Fall even years
HMP:7940	Primary Data and Mixed Methods	3 s.h.	Spring
HMP:7960	Analytical Issues in Health Services Research I	3 s.h.	Fall even years
HMP:7965	Analytical Issues in Health Services Research II	3 s.h.	Spring odd years
PCOL:4130	Drug Mechanisms and Actions	3 s.h.	Spring
PCOL:5136	Pharmacogenetics and Pharmacogenomics	1 s.h.	Spring
*Semester(s) offered subject to change due to enrollment, instructor availability, etc. Students should always check the course schedule at MyUI.uiowa.edu for the most up to date version of the course schedule.

Master’s in Clinical Investigation

Certificate in Translational and Clinical Investigation

Centers and Institutes

• Health Effectiveness Research Center
• Preventive Intervention Center 
• Institute for Clinical and Translational Science
• Holden Comprehensive Cancer Center

Research Resources

• SEER-Medicare Users Group
• Iowa Personal Health Record
• PCORnet Greater Plains Collaborative Iowa Research Core